The Blood Pill was planned to be used by Shangguan Xiu to increase his chance to form a Perfect Foundation, but the plan was ruined by Meng Hao. To concoct Blood Pills, Shangguan Xiu had surrounded three countries near Mount Daqing with a horrific spell, which sucked out a mortal's longevity.

It is a very cruel and inhumane pill, because it requires the blood of mortals. But because of its immoral requirements, it is suspected that the Blood Pill is highly beneficial to one's cultivation base in the Qi Condensation Stage.

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